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University of Rochester Technical Assoc-Sr (S) - 212462 in Rochester, New York

Technical Assoc-Sr (S)

Job ID



School of Medicine & Dentistry

Full/Part Time


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Full Time 40 hours Grade 054 Pediatric M&D Inf Diseases


9 AM-5:30 PM



Position Summary:

The Senior Technical Associate/Lab Manager will work closely with all lab members of the Gigliotti/Wright Lab and supervise the daily work of Research Technicians, and trainees (Fellows and students), Graduate students and Research Assistants to integrate the work of the lab into the existing lab structure and to ensure the smooth running of the laboratory and education of trainees. The Senior Technical Associate will have the overarching responsibility for supervision to ensure compliance, training, identifying and resolving issues. This support may include assisting others to design experiments, assist in performing the work and order materials as needed, collect and interpret data, plan future studies based upon those findings, and prepare written reports. S/he will ensure the laboratory is compliant with local and federal laws, and that proper health and safety practices are maintained particularly relevant to the work. S/he will share responsibility for ensuring that laboratory equipment is properly functioning and meeting appropriate standards; interact with service personnel; and make recommendations for repairing or replacing equipment as necessary.

The Senior Technical Associate is expected to be proficient at the lab bench. Candidates with experience in breeding and genotyping of mouse strains, small animal surgery, hybridoma production, antibody class switching , protein purification, Western blotting, ELISA,PCR, histology, cell culture, flow cytometry and cell sorting, or the ability and willingness to learn these skills will be preferred. She/he will assist with human biospecimen preparation and storage. The Senior Technical Associate will conduct quality assessments of all research efforts and support novel research efforts.


Pursues and maintains complex communication and supportive research efforts as needed to co-workers, students and collaborators in conjunction with the PI, to meet the research aims: to reduce lung injury in immune mouse models of infection with crossover to areas of human research efforts related Pneumocystis PcP with minimal supervision.

Writes and implements detailed laboratory protocols (SOPs) for research project directly related to primary project and evaluates protocols for other projects. Writes, maintains updated SOPs for Laboratory, ensuring website is current. Performs literature searches and updates PI and laboratory personnel on techniques relevant to Research efforts, Research Center findings and interactions and makes recommendations regarding future directions especially as related to future research directions.

Once trained on procedures used in the lab and the structure of the Project, performs laboratory tasks related to the study of immune lung injury and development of treatments or vaccines to reduce Lung injury as related to PcP, with technical independence and under broad long term and minimal short-term guidance from PI. Performs, in collaboration with other lab members and PI, autonomous research using independent technical judgment, collaborating with the PI on the design and analysis of complex experiments. Modifies and performs customized research experiments based on analysis of results.

Advise technical staff and junior trainees in day-to-day operations. In the absence of the PI, provides short to medium term direction to other lab members assisting in the design of experiments, analysis of data, and by making modifications in short term approaches based on these results. Make recommendations and advise principal investigator and other researchers regarding scientific techniques to be employed and offer suggestions in experiment design.

Responsible for overall supervision and operations of the Laboratory ensuring training, compliance, safety. Identifies issues, proposes resolutions and implements. Evaluates staff performances, completes performance assessments, interviews and makes hiring decisions. Identifies and resolves performance issues.

Assists faculty researchers in preparation and writing of annual reports and original grant submissions. Prepares laboratory budgets for grant proposals and laboratory projects. Analyzes data, prepares figures and writes methods and results summaries for publications. Participates in the preparation of publications at the level of co-author, critically edits draft writings.

Investigates funding opportunities and provides information as to the efficacy for submitting proposals. Packages preliminary data for use in funding applications. Ensures the laboratory prioritizes well and responds rapidly to changing opportunities for proposals and manuscripts. Writes initial proposals including gathering budgetary information and identifying collaborators, internal and external to the University, for review by PI.

Shares responsibility with other lab staff to oversee maintenance, management, and/or repair of equipment; coordinates ordering of supplies and equipment and trains people in the appropriate use of equipment. Has the ability to make decisions on purchases of supplies and equipment. Will perform in depth comparative research to obtain the best product at the best price and provide informed recommendations to the PI for decision making.

Participates in weekly lab meetings, seminars pertinent to laboratory goals, and scientific conferences and/or scientific meetings. Represents the PI on behalf of the laboratory and the research presenting data, analysis and status of research including disseminating and translating/analyzing national data connected to other research sites.

Oversees regulatory issues including biosafety, environmental health and radiation usage especially relevant to the lab. Responsible to implement changes, respond to issues, etc. Ensures that health and safety practices are maintained in accordance with University policy and the law. Directs and coordinates laboratory and equipment inspections working with Environmental Health and Safety and vendors.


Master’s degree with major course work in the field of assignment. With a Master’s Degree, a minimum 3 years of professional experience in the field of assignment. With the equivalent of a Master’s Degree in experience, training and education, 5 years in the field of assignment with some independent research experience; or an equivalent combination of experience, training and education.

Prefer degree in biology, biochemistry or microbiology and more than 2 years of academic research experience in molecular biology, biochemistry, microbiology using techniques of modern cell and molecular biology including RNA isolation, cell dissociation and isolation, cell culture, and flow cytometry. Strong computer, written and oral communication skills are required. The individual will be required to keep abreast of scientific literature related to immune lung injury in select mouse models of infection with Pneumocystis, PcP. Requires a high level of attention to detail, sense of commitment, organization and ability to multi-task in a fast-paced laboratory environment. Candidate must work well in a collaborative work environment. Prefer 5-10 years’ experience in research laboratory and lab management. Must have reliable/efficient transportation. May require travel to meetings, conferences or the like.

Expertise with maintaining databases, freezer inventory, protocols, equipment and accounting as required.

How To Apply

All applicants must apply online.

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