University of Rochester Technical Assoc I (S) in Rochester, New York


Full Time 40 hours Grade 051 Microbiology & Immunology M&D;




General Purpose:

Manage the Dewhurst lab: supervising junior staff and some trainees; overseeing assignment of lab space; overseeing all lab purchasing and expenditures; providing shared oversight of the lab budget; managing laboratory safety programs and interactions with internal regulatory committees; oversight of lab animal (mouse) colonies; performance of laboratory research including neuroAIDS related projects. Using independent judgment, develop and modify scientific protocols.

Specific Responsibilities:

Under the general guidance of the Laboratory Director, with latitude for exercising independent judgment, specific responsibilities will include:

  • Train and supervise junior staff and some trainees, troubleshooting and making recommendations to them for changes in protocols to assure their success.
  • Oversee all purchasing of research supplies and equipment, including placement of orders with vendors and oversight of laboratory supply inventories.Also, monitor/track all laboratory expenditures in consultation with the Department Senior Accountant, to ensure that expenses are charged to appropriate accounts and that expenses do not exceed available resources.Provide the Laboratory Director with regularly updated information on spending and available resources, and provide shared oversight of the lab budget.
  • Manage laboratory safety programs and interactions with internal regulatory committees.This includes leading laboratory safety training presentations for staff, students, postdocs and any new persons coming into the lab.In addition, maintain personnel training and laboratory safety records and interact with biosafety and vivarium staff.
  • Oversee laboratory animal (mouse) colonies, including breeding of transgenic mice, genotyping and general husbandry.
  • Oversee assignment of lab space to laboratory members, including part-time undergraduate trainees and summer students.
  • Maintain contact with outside research laboratories, vendors and technical representatives.Orient new personnel and visitors to the lab.
  • Perform hands-on laboratory research including performance of animal studies, using mice, to examine the virulence of influenza strains in vivo and to test the potential of attenuated virus strains to serve as potential vaccines and to protect against infectious virus challenge.Cell biology experiments will be performed using primary human cells, cultured mammalian cell lines and bacteria.Experimental analyses may include analysis of cytokine production (using ELISA, Luminex assays) and protein expression (immunoblot, immunohistochemistry, flow cytometry) by cells, as well as assays of cell survival and studies on HIV-1 replication.Molecular biology experiments will include assistance with production of recombinant proteins, and production of recombinant viral vectors.Must be able to develop and modify scientific protocols and to use independent judgment, where necessary, to modify protocols in order to carry out experiments and to meet special needs.
  • Analyze, evaluate and trouble shoot experimental data, and interpret results within the scope of the research; prepares reports and sections of grants, budgets and manuscripts for the Laboratory Director.Displays independence in problem solving.
  • Participate in scientific seminars.Prepare and present data, at laboratory meetings and at local/national research gatherings. Also, keep abreast of trends in the field by reading professional journals and attending relevant meetings and seminars.


  • A Bachelor's degree in a scientific or engineering discipline is required with a minimum of 1 years’ experience in a research laboratory environment (with emphasis on molecular and cellular biology).Ability to perform mathematical calculations using algebra and practically apply percentages, fractions, and ratios.Uses eyes, hands and fingers with skill.Requires the ability to speak and understand English language; follow instructions exactly, and record information accurately.Ability to work independently and safely using toxic chemicals.Ability to listen to, convey, or exchange information with other laboratory personnel.This position may entail prolonged periods of standing.

EOE Minorities/Females/Protected Veterans/Disabled

Job Title: Technical Assoc I (S)

Location: School of Medicine & Dentistry

Job ID: 208796

Regular/Temporary: Regular

Full/Part Time: Full-Time