University of Rochester Laboratory Technician IV (S) in Rochester, New York


Full Time 40 hours Grade 079 Microbiology & Immunology M&D;




Position Summary:

To perform overall lab management duties and to perform cell biology experiments using primary human cells, cultured mammalian cell lines, and infectious influenza. Works semi-independently using techniques in cell and molecular biology, and or neuroscience.

Typical Duties:

Performs administrative responsibilities to support the continuing operation of the laboratory. Duties will include ordering of supplies and animals, maintenance of supply and animal inventories, maintenance of personnel training and laboratory safety records, laboratory safety training for staff, students, postdocs and any new persons coming into the lab

Performs complex animal studies, using mice, to examine the virulence of influenza strains in vivo, and also to test the potential of attenuated virus strains to serve as potential vaccines, and to protect against infectious virus challenge. The candidate will be expected to supervise and manage the breeding and maintenance of the lab’s transgenic mouse colony.

Performs complex cell biology and molecular biology experiments using primary human cells, cultured mammalian cell lines, and infectious influenza virus. Cell biology experiments may include assays of influenza virus infection in cultured mammalian and avian cells, with analysis methods to include flow cytometry, fluorescence microscopy, luciferase assays, immunoblot assays, virus plaque assays and titrations, and generation of recombinant influenza viruses. Molecular biology experiments will include assistance with production of recombinant proteins, and production of recombinant viral vectors. Must be able to modify scientific protocols and to use independent judgment, where necessary, to modify protocols in order to carry out experiments.

Analyzes, evaluates and troubleshoots experimental data and interprets results within the scope of the research and prepares reports for PI. Independence in problem solving is highly encouraged.

Participates in scientific seminars. Prepares and presents data at laboratory meetings and at local/national research gatherings.

Maintains contact with outside research laboratories, vendors and technical representatives. Orients new personnel and visitors to the lab.


Operates complex scientific equipment. Performs routine maintenance of laboratory equipment such as cleaning and replacing parts and checking for malfunctions.


  • Associate’s Degree plus 4-5 years’ experience in microbiology and molecular biology, or equivalent combination of education and experience. A Bachelor’s Degree and previous instruction in virology and independent research is highly desirable.
  • Previous instruction in theoretical aspects of cell and molecular biology is highly desirable.
  • Ability to perform mathematical calculations using algebra and practically apply percentages, fractions, and ratios.
  • Uses eyes, hands and fingers with skill.
  • Ability to speak and understand the English language; follow instructions exactly, and record information accurately.
  • Ability to work independently and safely using toxic chemicals.
  • Ability to listen to, convey, or exchange information with other laboratory personnel.
  • This position may entail prolonged periods of standing.

EOE Minorities/Females/Protected Veterans/Disabled

Job Title: Laboratory Technician IV (S)

Location: School of Medicine & Dentistry

Job ID: 207932

Regular/Temporary: Regular

Full/Part Time: Full-Time